Cellularuptake相关论文
The use of small interfering RNAs(siRNAs)has been under investigation for the treatment of several unmet medical needs,i......
Toxicological effects of silica nanoparticles on human gastric cancer MGC80-3 cells and cervical ade
Silica nanoparticles (SNPs) have been used in several industries, and also been exploited for biomedical research as bio......
Gemcitabine (GEM) is the most potent anti-cancer drug for the treatment of pancreatic cancer.However,it undergoes rapid ......
Proteins play crucial functions inside cells and are promising tools for medical applications,including disease therapie......
Combating Drug Resistance in hepatocellular carcinoma cells through inhibition of ABC family protein
Multidrug resistance is an unavoidable obstacle in the development of anticancer research.Platinum(Pt)based complexes ha......
Protein Corona Influences Cellular Uptake of Gold Nanoparticles by Phagocytic and Non-phagocytic Cel
The interaction at nano-bio interface is a critical issue in designing safety nanomaterials for biomedical applications....
Cellular uptake enhancement and internalization pathways determination for intracellular polymeric p
Successful controlled release for intracellular delivery requires both sufficient cellular uptake and suitable internali......
Two-phase microfluidic droplet flows of self-crosslinking polymer for the synthesis of protein deliv
Modern biotechnology has led to the development of a large invaluable family of potential therapeutic proteins.These pro......
The uterine cervix carcinoma is one of the malignant diseases where platinum-based drugs such cisplatin are included in ......
Nanomaterials including carbon nanotubes (CNTs) have attracted intense interest and shown great potential for biomedical......
Enzyme-responsive asymmetric polymersomes with triggered apoptosis-mimicking flip-flop of cell-penet
Cytomimetic vesicles not only provide simplified models for investigation of the cell behaviors but also show a variety ......
large number of lead compounds have low solubility in water,which greatly hinders their clinical application.Recently,na......
Lipid-polymer hybrid nanoparticles with unique hybrid architecture have been widely applied on nanomedicine.Phospholipid......
Evaluating the Cellular Uptake Efficacy of Ferromagnetic Nanoparticles with or without A Protein-Cor
Light scattering properties of ferromagnetic nanoparticles(NPs)were combined with membrane fluorescence probe for unequi......
Development and evaluation of chitosan-based nanoparticles for enhanced bioavailability of paclitaxe
Polymeric nanoparticles have been increasingly investigated as promising nanocarriers for oral drug delivery.Based on th......
In vitro/in vivo transdermal delivery study of NLCs loaded with the alkaloidal extract from Aconitum
The aims of the present study were to evaluate the microstructure and study the in vitro/in vivo transdermal delivery of......
A novel lanreotide-modified micelle system targets paclitaxel to the tumors with overexpression of s
Many tumor cells specifically overexpress somatostatin receptors, in particular, subtype 2 (SSTR2). Lanreotide, a somato......
To develop the proper renal targeting carrier for clinical therapy, human serum albumin, as starting material, was first......
Multifunctional Protein Kinase CK2 Inhibitor Loaded Gold Nanoparticles for Simultaneous Cancer-Targe
Objective: Protein kinase CK2 is a multipotential serine/threonine kinase and plays multiple roles in the regulation of ......
Redox and pH dual responsive poly (amidoamine)dendrimer-poly (ethylene glycol) conjugates for intrac
To solve the contradiction between long circulation time and effective intracellular drug release, redox and pH-responsi......
Particle size effect of curcumin nanosuspensions on the in-vitro anticancer activity,cellular uptake
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Folic acid and TAT peptide co-modified liposomes achieve highly efficient cellular uptake in vitro a
Two essential characteristics of therapeutic nanocarriers are their rapid uptake into, and their specific recognition by......
OBJECTIVE To investigate the preparation and characterization of α-Hederin-loaded galactosylated chitosan nanoparticle ......
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Recent experiments have pointed out that cellular uptake is strongly dependent on the physical dimensions of endocytosed......
Objective: To investigate the effect of phospholipid composition on cellular uptake of lipid-PLGA hybrid nanoparticles.M......
Improved cytotoxicity of Paclitaxel loaded in nanostructured lipid carriers by intracellular deliver
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Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepa
Recently,peptide drugs have evolved into mainstream therapeutics,representing a significant portion of the pharmaceutica......
Recent experiments have pointed out the cellular uptake is strongly dependent on the physical dimensions of endocytosed ......
Studies have shown that two novel ruthenium(Ⅱ) Polypyridyl complexes hydrophobic ancillary ligands have relatively stro......
Synchrotron radiation-based techniques for revealing cellular trafficking and transformation of nano
Nowadays,nanotechnology has experienced a rapid development and many different nanoparticles are incorporated in man......
Mitochondrial transplantation strategies as potential therapeutics for central nervous system trauma
Mitochondria are essential cellular organelles critical for generating adenosine triphosphate for cellular homeostasis, ......
